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Get emergency medical aid When you have signs of an allergic reaction to codeine: hives; tough breathing; swelling of the confront, lips, tongue, or throat.
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The narcotic antagonist, naloxone hydrochloride, might be administered when substantial respiratory depression takes place with promethazine and codeine; any depressant results of promethazine usually are not reversed with naloxone. Diazepam might be employed to regulate convulsions. Avoid analeptics, which can trigger convulsions. Acidosis and electrolyte losses really should be corrected. An increase in temperature or pulmonary complications may signal the need for establishment of antibiotic therapy.
Prevent the usage of Promethazine with Codeine Oral Resolution in clients with head damage, intracranial lesions, or simply a pre-existing increase in intracranial tension. In sufferers who can be prone to the intracranial consequences of CO 2 retention (eg., People with evidence of amplified intracranial force or Mind tumors), Promethazine with Codeine Oral Answer may cut down respiratory drive, as well as resultant CO two retention can even more enhance read more intracranial strain.
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Narcotic analgesics or cough suppressants, like codeine, should not be used in asthmatic patients (see CONTRAINDICATIONS). Nor ought to they be used in acute febrile get more info illness associated with successful cough or in Long-term respiratory disorder wherever interference with power to very clear the tracheobronchial tree of secretions would have a deleterious impact on the affected individual's respiratory check here operate.
The result of promethazine and/or codeine on the later on growth and improvement of your newborn is not known.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals fewer than here 6 years of age, since The mix could cause deadly respiratory despair On this age inhabitants. It is crucial that promethazine with codeine syrup is calculated by having an accurate measuring system (see Safeguards-Information and facts For Patients).
Explain to your doctor In case your cough will not get well in five times. Also, notify your doctor In the event your problem gets worse, or For those who have a headache that doesn't go away, fever, or rash. These may be indicators of a serious healthcare issue and should be checked by a health care provider.
In the investigation, an agent was contacted by a “Gwendolyn Cox,” who evidently misspoke and explained her last identify was “White,” when asked. Court more info docket documents say “Cox” couldn't supply her age or handle, only her birth thirty day period and day.
Drug interactions could change how your prescription drugs function or boost your risk for serious Unintended effects. This document won't have all probable drug interactions.
When physicians prescribe codeine-containing medications, they ought to pick the least expensive efficient dose to the shortest timeframe and may advise their people about these hazards along with the indications of morphine overdose (see Safeguards - Nursing Moms).
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